CD4+ T cells contribute to neurodegeneration in Lewy body dementia.

David Gate,Emma Tapp,Olivia Leventhal,Marian Shahid,Tim J. Nonninger,Andrew C. Yang,Katharina Strempfl,Michael S. Unger,Tobias Fehlmann,Hamilton Oh,Divya Channappa,Victor W. Henderson,Andreas Keller,Ludwig Aigner,Douglas Galasko,Mark M. Davis,Kathleen L. Poston,Tony Wyss-Coray

CD4+ T cells contribute to neurodegeneration in Lewy body dementia.

2021

David Gate
Emma Tapp
Olivia Leventhal
Marian Shahid
Tim J. Nonninger
Andrew C. Yang
Katharina Strempfl
Michael S. Unger
Tobias Fehlmann
Hamilton Oh
Divya Channappa
Victor W. Henderson
Andreas Keller
Ludwig Aigner
Douglas Galasko
Mark M. Davis
Kathleen L. Poston
Tony Wyss-Coray

Recent studies indicate that the adaptive immune system plays a role in Lewy body dementia (LBD). However, the mechanism regulating T cell brain homing in LBD is unknown. Here, we observed T cells ...

Keywords:

Neuroscience
Lewy body
Dementia
Neurodegeneration
homing
T cell
Acquired immune system
Mechanism (biology)
Medicine

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