Infantile Hemangioendothelioma Associated with Bone Marrow Dysfunction

A 5-month-old-girl had hepatomegaly and severe anemia. Based on the multiple imaging studies, hemangioendothelioma was suspected. Wedge resection of the liver and hepatic artery ligation were performed. The peripheral blood film showed pancytopenia, and the myelogram showed markedly reduced erythroid series and myeloid predominance with shift to the left. The correlation between hemangioenothelioma and bone marrow dysfunction is unknown. As far as we know, this is the first report of infantile hemangioendothelioma associated with bone marrow dysfunction.