An Increased Throughput Method for the Determination of Partition Coefficients

Laure Hitzel,Alan P. Watt,Karen L Locker

An Increased Throughput Method for the Determination of Partition Coefficients

2000

Laure Hitzel
Alan P. Watt
Karen L Locker

Purpose. To present an increased throughput automated shake-flask method for the direct determination of the partition coefficients of solutes between octan-1-ol and buffer.

Keywords:

Quantitative analysis (chemistry)
Partition coefficient
High-performance liquid chromatography
Chemistry
Gradient method
Throughput
Analytical chemistry
Reversed-phase chromatography
Chromatography
pharmacology toxicology

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