Plasmablastic lymphoma of the anus: a case report

Plasmablastic lymphoma (PBL) is a rare variant of diffuse large B-cell lymphoma which has been most commonly reported in jaw and oral cavity in Human Immunodeficiency Virus (HIV) infected patients. A handful of cases have been reported in the extra-oral sites. Plasmablastic lymphomas should be differentiated from other large cell lymphomas as these lymphomas have very short survival and poor response to chemotherapy. We present a case of PBL in an HIV infected patient with history of recurrent anal fistulotomies.