ER stress abrogates the immunosuppressive effect of IL-10 on human macrophages through inhibition of STAT3 activation

Ivo S. Hansen,Josca M. Schoonejans,Lathees Sritharan,Johan A. van Burgsteden,Carmen A. Ambarus,Dominique Baeten,Jeroen den Dunnen

ER stress abrogates the immunosuppressive effect of IL-10 on human macrophages through inhibition of STAT3 activation

2019

Ivo S. Hansen
Josca M. Schoonejans
Lathees Sritharan
Johan A. van Burgsteden
Carmen A. Ambarus
Dominique Baeten
Jeroen den Dunnen

Objective and design To determine whether ER stress affects the inhibitory pathways of the human immune system, particularly the immunosuppressive effect of IL-10 on macrophages.

Keywords:

Immunosuppressive effect
Interleukin 10
Cancer research
Biochemistry
Unfolded protein response
STAT3
Diabetes mellitus
Biology
Inflammation
Tunicamycin
Immune system
SOCS3
Cytokine
Cell biology
Signal transduction

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations