The aplication of cyanoacrilate surgical glue on skin suture in rats

Astractrs: To compare the use of a new cyanoacrylate-based surgical glue and suture with sepa-rate points in skin wounds closure. Mets: Thirty-six rats were subjected to a 4cm dorsal longitudinal incision. Twelve were sub-jected to simple suture with polyamide 6-0, 12 rats underwent wall synthesis using Dermabond® and 12 was performed cutaneous synthesis with N-2-Butyl-Cyanoacrylate. Twelve of each group AµšZv]I}všZAvšZ‰}š}‰ŒŸ ACUšZ]Œo}}Ašlvš}]}Zu]oššvoCŒ}(l]vv µ µšv}µŸµµŒŒ}µv]vPšZµŒP]oŒAŒv}uoC]A]in two segments, to the submission of tension tests and to histological study.Rsts: dZŒAŒv}]Pv].vš]+ŒvšAvPŒ }µ‰~‰EiXinX/všZ }LŒu]šZŒAu}ŒšC‰/}ooPv‰Œ}µŸ}v]vPŒ}µ‰/~‰DiXinUPŒ}µ‰//v///A]u]oŒŒrµoš~‰EiXinX/všZ }u‰šŒu]UooiPŒ}µ‰Z}A]u]oŒ Œµoš~‰EiXinXdZ]}uZv]ošµCA]u]oŒ]šCšAvšZPoµPŒ}µ‰~‰EiXinµššZPŒ}µ‰///‰Œ}Aš}]+Œvš(Œ}ušZ}šZŒZA]vPZ]PZŒŒ]šv~‰EiXinXCcsi: dZ]Poµ}v}šµvC]vGuuŸ}v}Œ l]vCvZ‰Ÿ š}AE]]šCXW}oCu]sutures are more resistant and the glue should be used alone only in less tension are-as.Ke rs: Collagen. Wound Healing. Cyanoacrylates. Rats.