Abstract 122: Deletion of Gstm1 Results in Poor Survival and Exaggerated Kidney Injury Associated With Increased Oxidative Stress and Apoptosis in a Mouse Model of Chronic Kidney Disease

In humans, a common deletion variant of the GSTM1 gene, the GSTM1(0) null allele, results in decreased GSTM1 enzymatic activity and is associated with higher levels of oxidative stress. We reported...