ADDITIVITY OF NEBIVOLOL/VALSARTAN SINGLE-PILL COMBINATIONS VERSUS OTHER APPROVED SINGLE-PILL COMBINATIONS FOR HYPERTENSION

Background: The single-pill combination (SPC) comprising nebivolol (5 mg), a vasodilatory β1-selective antagonist/ β3 agonist, and valsartan (80 mg), an angiotensin receptor blocker, is the only FDA-approved β-blocker/renin-angiotensin-aldosterone system (RAAS) inhibitor SPC for hypertension.