Azoospermia after testosterone gel treatment

A case report presented azoospermia in 30 y.o. man after 4 months of 50 mg daily dose testosterone gel treatment. The absence of sperm in ejaculate urged interruption of couple infertility treatment by means of IVF, oocytes cryopreservation was performed. Initiation of testosterone replacement monotherapy should be avoided in men wishing to preserve fertility.