Clinical prediction value of revised Geneva scores for PE-COPD

Objective To understand the prevalence and clinical characteristic of chronic obstructive pulmonary disease associatied with pulmonary embolism (PE-COPD),analyze the predictive value of Geneva scores for it and correlation between Geneva scores and lung function scale as well as scale of blood gas analysis.Methods Retrospectively survey for in patient medical database of PE patients who were discharged from Tianjin Medical University Genenral Hospital from February,2009 to December,2011.Each PE-COPD patient was applied Geneva scores,and receiver operating characteristic (ROC) carve was used to evalute its clinical value for PE-COPD.Results Of 127 patients with a conformed diagnosis of acute PE,the amount of PE.COPD patients were 16 (17.6％,95％ CI 6.8％-18.4％).The area under curve (AUC) of the ROC curve in Geneva scores predicted PE COPD was 0.759(P ＜0.05).95％ confidence interval (CI) was 0.654-0.873.The optimal cutoff value was 5.5,the score more than 5.5 with a sensitivity of 81.3％ and specificity of 63.1％,then FEV1％pred and PaO2 of PE-COPD patients were negtively correlated with Geneva scores (P ＜0.05),but FEV1/FVC％ and PaCO2 as well as PH was no correlated with it (P ＞0.05).Conclusions Geneva scores being certain predictive value of PE COPD,in particular,COPD patient of poor lung function and severe hypoxemia has higher clinical probabolity of PE. Key words: Pulmonary embolism; Chronic obstructive pulmonary disease; Geneva scores