OUTCOMES OF DRUG-INDUCED ACUTE PANCREATITIS: A TEN-YEAR EXPERIENCE OF AN ACADEMIC CENTER.

BACKGROUND Drug-induced pancreatitis is an unexplored entity. METHODS Retrospective cohort study conducted at a referral center. Patients with drug-induced acute pancreatitis between 2008-2018 were included. Baseline patients´ characteristics, involved drugs, clinical course and recurrence were analyzed. RESULTS Drug-induced pancreatitis represented 2.8% of acute pancreatitis (47/1665), and 18 different involved drugs were identified (thiopurines 61.8%). Latency period was less than one month in 87.2%. Pancreatitis was mild in 89.3%. Recurrence risk was 2.3%. CONCLUSION Drugs are a rare cause of pancreatitis, which mostly occurs within the first month of treatment, is usually mild and associates a low risk of recurrence.