Nonsteroidal Anti-inflammatory Drugs Associated Peptic Ulcer Bleeding with 69 Cases Analysis

【Objective】 To investigate the clinical characters of nonsteroidal anti-inflammatory drugs(NSAID) associated peptic ulcer bleeding through retrospective analysis.【Methods】Four hundred ninety-nine patients who were hospitalized in our wards diagnosed as peptic ulcer bleeding from February 2007 to January 2011 were divided into two groups according to taking NSAID or not.【Results】 Sixty-nine cases(13.8%) with NSAID associated peptic ulcer bleeding were included.Compared with 430 cases without NSAID associated,there were significant differences in age,gender,co-administration with anti-coagulant drugs or steroids,location and amount of ulcers,severity of anemia in elder patients(P 0.05).【Conclusions】 NSAID associated peptic ulcer bleeding mainly occurred in stomach with more multiple ulcers,while patients seldom complained of epigastric pains.These ulcers were more common in 60-year-old or above patients,who suffered from more severe anemia.