Azacitidine freeze-dried preparation and preparation method thereof

The invention belongs to the field of pharmaceutical preparations and in particular relates to an azacitidine freeze-dried preparation with stable proprieties. The active ingredient of the azacitidine freeze-dried preparation is a treatment effective amount of azacitidine; a solution contains an organic solvent, a freeze-drying proppant and injection water before freeze-drying; the organic solvent is selected from ethanol, isopropanol, methanol or a mixed solution thereof in any ratio, and preferably is ethanol; and the usage amount of the organic solvent is 0.3-6.0% of the total volume of the solution before freeze-drying. The invention also provides a preparation method of the azacitidine freeze-dried preparation which is simple in process, is suitable for scale production and can be clinically used.