Tumor pathological and immunological changes in HER2+ metastatic breast cancer (MBC) following trastuzumab combined with expanded and activated autologous natural killer (NK) cell infusion.

Kritika Yadav,Noriko Shimasaki,Samuel Guan Wei Ow,Andrea Li Ann Wong,Joline Si Jing Lim,Priscillia Koe,Liang Piu Koh,Lip Kun Tan,Boon C. Goh,Dario Campana,Soo-Chin Lee

Tumor pathological and immunological changes in HER2+ metastatic breast cancer (MBC) following trastuzumab combined with expanded and activated autologous natural killer (NK) cell infusion.

2019

Kritika Yadav
Noriko Shimasaki
Samuel Guan Wei Ow
Andrea Li Ann Wong
Joline Si Jing Lim
Priscillia Koe
Liang Piu Koh
Lip Kun Tan
Boon C. Goh
Dario Campana
Soo-Chin Lee

e12511Background: A central mechanism for the anti-tumor activity of Trastuzumab, a HER2 monoclonal antibody, against HER2+ tumors is induction of antibody dependent cell cytotoxicity (ADCC) mediat...

Keywords:

Cell
Cancer research
Trastuzumab
Pathological
Pathology
Medicine
Metastatic breast cancer
HER2 Monoclonal Antibody
Antibody-dependent cell-mediated cytotoxicity
Antibody-dependent cell cytotoxicity

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