Improved Large-scale Synthesis of 5-(Perylen-3-ylethynyl)-arabino-uridine (aUY11), the Broad-Spectrum Antiviral

Rigid amphipathic fusion inhibitors (RAFIs), 5-arylethynyl-uracil nucleosides with bulky aryl groups, constitute a class of compounds active against enveloped viruses.1 Derivatives of perylene, a p...