Relationship Among Mothers' Glycemic Level, Periodontitis, and Birth Weight

Background: The aim of this study is to determine the influence of glycemic level on the relationship between periodontitis and low birth weight (LBW).Methods: A case-control study was conducted with 372 females divided into cases (109 mothers of newborns with birth weight <2,500 g) and controls (263 mothers of newborns with birth weight ≥2,500 g). The birth weight of children was obtained from medical records, whereas information on sociodemographic, lifestyle, and health characteristics of the participants was obtained through an interview. Glycated hemoglobin (HbA1c) levels were measured, and probing depth, clinical attachment levels, and bleeding on probing were used to determine the periodontal status. Results were analyzed using logistic regression.Results: The likelihood of having children with LBW among the mothers with periodontitis was six times greater than that observed among mothers without periodontitis (adjusted odds ratio [ORadjusted] = 6.02, 95% confidence interval [CI] = 2.47 to 15.17), ...