Tumor infiltration and cytokine biomarkers of prostate stem cell antigen (PSCA)-directed GOCAR-T cells in patients with advanced pancreatic tumors.

Joanne Shaw,Brandon Ballard,Xiaohui Yi,Aditya Malankar,Matthew R. Collinson-Pautz,Carlos Becerra,Joseph Paul Woodard,Aaron E. Foster

Tumor infiltration and cytokine biomarkers of prostate stem cell antigen (PSCA)-directed GOCAR-T cells in patients with advanced pancreatic tumors.

2020

Joanne Shaw
Brandon Ballard
Xiaohui Yi
Aditya Malankar
Matthew R. Collinson-Pautz
Carlos Becerra
Joseph Paul Woodard
Aaron E. Foster

734Background: PSCA is a cell surface protein overexpressed in approximately 60% of pancreatic cancers. BPX-601 is an autologous GOCAR-T cell therapy engineered to express a PSCA-CD3ζ CAR and the M...

Keywords:

Cytokine
Prostate Stem Cell Antigen
Medicine
Biomarker (medicine)
Pathology
in patient
surface protein
Cell therapy

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