Untersuchung von Biomarkern bei Patienten mit Anca-assoziierter Vaskulitis.
2018
ANCA-associated vasculitides (AAV) are the most frequent types of primary small-vessel vasculitides
according to the revised Chapel Hill consensus conference nomenclature from 2012 [1]. AAV
are represented by at least three distinct disorders, each characterized by inflammatory damage
of small blood vessels including arterioles, capillaries and venules, and each variably associated
with peripheral circulating antineutrophil cytoplasmic antibodies (ANCA) of different antigen affinity. The patients clinical symptomes, therapeutic response and the outcome is very heterogen. Therefore we investigated profling zytokines and compare to epidemiological and clinical factors, progress of disease and therapeutic response.
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