L'Excrétion rénale du citrate chez le chien

Clearance measurements were made in 15 dogs in order to study the urinary citrate excretion. The citrate determination is performed in blood plasma and urine, with an enzymatic specific method. The authors find that more than 99% of the citrate filtered through the glomerulus is reabsorbed. The greater sensitivity, specificity and accuracy of the enzymatic method, which has been compared with the usual chemical methods, may explain the discrepancy between these data and the results published by other authors. These results are consistent with the hypothesis that citrate is filtered, reabsorbed and not secreted by the tubule in the dog.