Comqarison on the consumption of propofol with laparoscopic esophageal hiatal hernia repair between patients of Uygur and Han nationalities

Objective To comqarison of the consumption of propofol with Laparoscopic Esophageal Hiatal Hernia Repair between patients of Uygur and Han nationalities.within scopes of the basic value plus or minus 20%.The consumption of propofol bispectral index (BIS),mean arterial pressure(MAP) and heart rate (HR) values at just at the anesthesia induction(T0), pneumoperitoneum(T1), 1~20 min after pneumoperitoneum(T2), 21~40 min after pneumoperitoneum (T3), 41~60 min after pneumoperitoneum(T4), 61~80 min after pneumoperitoneum(T5), 81~100 min after pneumoperitoneum(T6), 101~120 min after pneumoperitoneum(T7); 121~1400 min after pneumoperitoneum(T8), 141 min after pneumoperitoneum to stopping pneumoperitoneum(T9) of the two groups were observed and recorded． Results The consumption of propofol at T0 time segments no statistical difference between the two groups(P＞0.05); At T1~T9 time segments, the consumption of propofol in the Uygur group were significantly higher than those in the Han group(P＜0.05); The MAP and HR at T1~T9 time segments no statistical difference between the two groups (P＞0.05). Conclusions The consumption of propofol in Han nationalities is higher to that in Uighurs, which may through Genetic polymorphism of metabolic enzyme gene.