Explore the definition of adenocarcinoma of esophagogastric junction

Adenocarcinoma of esophagogastric junction is located in the special anatomical location, which is different from esophageal cancer and gastric cancer in biological characteristics. Therefore, the definition, clinical classification and tumor staging are controversial. Currently the classification of Siewert is accepted by worldwide. Meanwhile, there is a relatively independent TNM staging based on the tumor site, this TNM stage can guide subsequent treatment accurately and judge prognosis. Thus, clinicians need to further study about the definition of adenocarcinama of esophagogastric junction and esophagogastric junction, clinical classification and tumor stage. In addition, we expect to perform basic and clinical research in future to get more high level evidence in order to provide treatment accurately for patients. Key words: Esophagogastric junction; Adenocarcinoma; Neoplasm staging; Clinical classification