PI3K Regulatory Subunits Lose Control in Cancer
2009
The PI3K signaling axis is frequently activated in cancer resulting from inactivation of its negative regulator PTEN or activating mutations of the p110α catalytic subunit of PI3K. In this issue of Cancer Cell, Jaiswal et al. report that mutations in the p85α regulatory subunit of PI3K can also activate this pathway in cancer.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
9
References
24
Citations
NaN
KQI