Die humane Knochenmarkszellkultur - Eine sensitive Methode zur Beurteilung der Biokompatibilität von Materialien, die in der Orthopädie verwendet werden

: The objective of the study was to develop a test system to determine the cytotoxicity and biocompatibility of different biomaterials used in orthopedic surgery. This system was based on the use of a human bone marrow cell culture and the purpose was to find a screening method as a alternative to early animal experimental methods. The established human bone marrow cell culture has certain advantages when compared with other cell culture models. The result demonstrated a high conformity with animal experimental results.