Clinical Characteristics of Patients with Gastroesophageal Reflux Disease Refractory to Proton Pump Inhibitors and the Effects of Switching to 20 mg Esomeprazole on Reflux Symptoms and Quality of Life

Fuminao Takeshima,Keiichi Hashiguchi,Yasunori Onitsuka,Ken Tanigawa,Hitomi Minami,Kayoko Matsushima,Yuko Akazawa,Ken Shiozawa,Naoyuki Yamaguchi,Naota Taura,Ken Ohnita,Tatsuki Ichikawa,Hajime Isomoto,Kazuhiko Nakao

Clinical Characteristics of Patients with Gastroesophageal Reflux Disease Refractory to Proton Pump Inhibitors and the Effects of Switching to 20 mg Esomeprazole on Reflux Symptoms and Quality of Life

2015

Fuminao Takeshima
Keiichi Hashiguchi
Yasunori Onitsuka
Ken Tanigawa
Hitomi Minami
Kayoko Matsushima
Yuko Akazawa
Ken Shiozawa
Naoyuki Yamaguchi
Naota Taura
Ken Ohnita
Tatsuki Ichikawa
Hajime Isomoto
Kazuhiko Nakao

Background Refractory gastroesophageal reflux disease (GERD) may deteriorate patient quality of life (QOL) despite proton pump inhibitor (PPI) therapy.

Keywords:

Endocrinology
Internal medicine
Esomeprazole
Medicine
Disease
GERD
Surgery
Proton-pump inhibitor
Diabetes mellitus
Gastroenterology
Quality of life
Refractory
Severity of illness
Reflux

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