Radiation Oncology of Lung Cancer: Why We Fail(ed) in Clinical Research?

Clinical research in radiation oncology of lung cancer can bring important advances in the field of optimized treatment approaches in this disease. However, such a research has been a subject of many controversies, in particular in the light of lack of adequate number and quality of clinical trials which could have changed our standard policies. To address the comprehensive issue of clinical research in radiation oncology of lung cancer, several aspects will be considered: general aspects of clinical research generals, clinical failures, and some of existing, rather controversial issues identified. Finally, some of possible solutions for the current, grossly unfavorable, situation will be discussed.