Two Cases Of Aggressive Squamous Cell Cervical Cancer

Background: Cervical cancer is an important cause of mortality worldwide. Screening programs are well established. The authors report two cases of highly aggressive squamous cell cervical cancers highlighting important issues. Case Reports: The first case was a IIB FIGO stage cervical cancer in a 20-year-old woman. The second was a carcinoma in situ treated with loop electrosurgical excision procedure (LEEP), in which follow-up failed to diagnose progression to IVA FIGO stage in a 15-month period. Discussion: The first case alerts to the importance of beginning cervical cancer screening after sexual activity initiation and that cytologic abnormalities in adolescents mandate close follow-up. Both cases alert to the fact that some squamous cell cervical cancers may behave in highly aggressive manners so current guidelines may fail to prevent their progression, even in immunocompetent patients.