Histiocitosis de células de Langerhans: Reporte de caso y revisión de la literatura

Histiocytoses comprises a heterogeneous group of inflammatory diseases for which dendritic cells and macrophages are the main cellular components. The inflammatory infiltrate can affect the skin and other organs, and clinical outcome varies from mild to lethal depending on the involved cell subset and multisystemic commitment. Delay in diagnosis may occur due to its non-specific presentation, and probably to a low suspicion on the part of the clinician. We report the case of an infant who, despite multiple consultations with nonspecific but characteristic symptoms of the disease, was only able to diagnose thanks to histopathological findings.