P.1.020 The role of tachykinin receptor 1 gene (TACR1), estrogen alpha and oxytocin receptor genes (ESR1, OXTR) in variation of personality traits

drinking water. The rest NaCl (controls) and PCP groups have received drinking water. BMD, bone mineral content (BMC) and fat mass were measured in vivo by dual X ray absorptiometry (DXA) on PN60 and PN98. The expression of GR and pGR was examined on PN98 by Western blot. Results of DXA measurements are presented in Table 1. Western blot analysis has shown significantly decreased expression of GR in cortex of PCP, NaCl-H and PCPH groups and also in hippocampus of PCP and NaClH groups. Increased GR expression was noticed in hippocampus in NaCl-C group. The expression of pGR was decreased only in cortex of PCP group, while there was a significant increase in cortex of PCP-H and PCP-C groups. Increased expression of pGR in hippocampus was seen in PCP, PCP-H, NaCl-C and PCP-C groups.