Method for diagnosing inflammatory respiratory diseases using outer membrane vesicles derived from bacteria

2016 
The present invention relates to a method for diagnosing inflammatory respiratory diseases using outer membrane vesicles derived from bacteria and, more specifically, to a method for diagnosing asthma, chronic obstructive pulmonary disease, and lung cancer by measuring specific antibodies to outer membrane vesicles derived from bacteria existing in indoor dust or to proteins derived from the outer membrane vesicles. The outer membrane vesicles derived from Staphylococcus spp., Acinetobacter spp., Pseudomonas spp., and Enterobacter spp., which exist in large quantities in dust in the indoor air, may cause inflammatory respiratory diseases, and thus the present invention can be favorably used as a method for diagnosing asthma, chronic obstructive pulmonary disease, and lung cancer, by measuring specific antibodies to outer membrane vesicles/proteins derived from the bacteria in patient samples.
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