Development of a bioanalytical method for an antisense therapeutic using high-resolution mass spectrometry.

Yuchen Sun,Shin-ichiro Nitta,Kosuke Saito,Ryuta Hosogai,Keiko Nakai,Ryoya Goda,Masaaki Kakehi,Kazuyuki Murata,Takeru Yamaguchi,Takeshi Okuzono,Shinichi Yamane,Yoshimasa Enoki,Mitsuhiko Kawabata,Kentaro Takahara,Shimpei Sato,Tokuyuki Yoshida,Takao Inoue,Yoshiro Saito

Development of a bioanalytical method for an antisense therapeutic using high-resolution mass spectrometry.

2020

Yuchen Sun
Shin-ichiro Nitta
Kosuke Saito
Ryuta Hosogai
Keiko Nakai
Ryoya Goda
Masaaki Kakehi
Kazuyuki Murata
Takeru Yamaguchi
Takeshi Okuzono
Shinichi Yamane
Yoshimasa Enoki
Mitsuhiko Kawabata
Kentaro Takahara
Shimpei Sato
Tokuyuki Yoshida
Takao Inoue
Yoshiro Saito

Background: Ion-pairing reverse-phase LC coupled with high-resolution mass spectrometry (IP-LC/HRMS) has gained attention in oligonucleotide therapeutic bioanalyses owing to its high sensitivity an...

Keywords:

antisense oligonucleotide
Chromatography
Oligonucleotide
Bioanalysis
Mass spectrometry
Sense (molecular biology)
Chemistry
Resolution (mass spectrometry)

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations