Design, Synthesis and Structure—Activity Relationship of Novel RXR‐Selective Modulators.

Pierre-Yves Michellys,Jennifer D'Arrigo,Timothy Alan Grese,Donald S. Karanewsky,Mark D. Leibowitz,Dale A. Mais,Christopher M. Mapes,Anne Reifel Miller,Deepa Rungta,Marcus F. Boehm

Design, Synthesis and Structure—Activity Relationship of Novel RXR‐Selective Modulators.

2004

Pierre-Yves Michellys
Jennifer D'Arrigo
Timothy Alan Grese
Donald S. Karanewsky
Mark D. Leibowitz
Dale A. Mais
Christopher M. Mapes
Anne Reifel Miller
Deepa Rungta
Marcus F. Boehm

The synthesis and in vitro characterization of novel RXR-selective ligands possessing various substituted 1-benzofuran or 1-benzothiophene moieties are described.

Keywords:

Retinoid X receptor
Structure–activity relationship
Chemistry
Organic chemistry
design synthesis

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