Model of Interaction Between TiO2 Nanostructures and Bovine Leucosis Proteins in Photoluminescence Based Immunosensor

A model of interaction between photoluminescent TiO2 nanoparticles and Bovine Leucosis proteins gp51 during the formation of optical immunosensor for the determination of gp51 antibodies has been proposed. The main reason of the changes in the photoluminescence (PL) spectra (i.e. PL maxima shifts and PL intensity variations) as a result of Bovine Leucosis proteins adsorption on the surface of TiO2 thin film is an electrostatic interaction between the TiO2 surface charge and partial uncompensated charges of gp51 proteins.