INHERITED DIFFERENCES AND DRUG-MEDIATED INHIBITION OF HYDROCODONE METABOLISM IN PATIENTS FOLLOWING LOWER EXTREMITY ORTHOPAEDIC SURGERY

Erik A. Korte,A.L. Malkani,Jeremy Gaskins,B. Hartley,Loralie J. Langman,Paul J. Jannetto,Gwendolyn A. McMillin,C. Maluf,Saeed A. Jortani

INHERITED DIFFERENCES AND DRUG-MEDIATED INHIBITION OF HYDROCODONE METABOLISM IN PATIENTS FOLLOWING LOWER EXTREMITY ORTHOPAEDIC SURGERY

2019

Erik A. Korte
A.L. Malkani
Jeremy Gaskins
B. Hartley
Loralie J. Langman
Paul J. Jannetto
Gwendolyn A. McMillin
C. Maluf
Saeed A. Jortani

Introduction Insufficient pain control following lower extremity surgery can increase length of stay, readmission rates, and impair postoperative outcome. It has been shown that CYP2D6 genotypes pr...

Keywords:

Anesthesia
postoperative outcome
Hydrocodone
pain control
in patient
Orthopedic surgery
CYP2D6
Drug
Medicine
Lower extremity surgery

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