Interplay of Steric Hindrance and Hydrogen Bonding To Restrict Mono-O-substitutedp-tert-Butylcalix[6]arenes in Cone Conformation

The simple mono-O-benzyl-p-tert-butylcalix[6]arene (2a) has been reported to display a cone conformation with a slow inversion rate at room temperature. Here, a series of mono-O-substituted p-tert-...