Detection of HbA1c in Blood Using Diode Laser (491) nm

Laser radiation is widely used in several applications like medicine, biology and industry. Laser biosensor is one of the tools in the biological applications. A laser biosensor is designed with different lengths of solid core photonic crystal fibers (LMA-10) (1.5cm, 1cm and 0.5cm) to be used for different tests. For the blood test, the highest sensitivity of 153 ABS/RIU was found for the (1.5cm) length. Moreover, the biosensor was used for the detection of HbA1c for the diagnosis of diabetes being a recognized valuable tool in diabetes management. Blood samples been taken from healthy people and others suffering from diabetes people. The results showed that the presence of diabetes led to increasing the output intensity of the laser beam as a results of enhancing the nonlinearity . The sensitivities of diabetes is 28.934 ABS/ RIU.