Urinary concentration and clearance indicators in pregnant women with gestosis

: Comparative evaluation of renal performance was conducted in 68 pregnant patients with nephropathies, stages I-II (first group) and in 53 pregnant females with nephropathy, stage III, associated with eclampsia (second group). Out of those 53 women, 28 patients suffered from combined gestosis in presence of chronic pyelonephritis and 25, in presence of chronic arterial hypertension. 20 females with normal pregnancy served as controls. In those with pregnancy complicated by nephropathies, stage I-II, the author revealed higher levels of blood plasma osmolality and its constituents in parallel with a significant decrease in concentration and clearance parameters of renal function. The latter resulted in statistically reliable increase in the urine concentration and clearance values. To avoid errors in the infusion therapy it was found necessary to carry out testing of renal functioning with the use of dosaged fluid load.