PMM.65 A Case Report of Takayasu’s arteritis with pregnancy associated hypertension

Background Takayasu’s arteritis is a chronic idiopathic arteritis affecting the aorta and its primary branches. The symptoms of the disease are varied and patients can present asymptomatically with impalpable pulses. The incidence of Takayasu’s is higher in females than that of males, and the disease most commonly presents between ages 15 to 30. Pregnancy is only recommended in patient’s whose disease is in remission. Due to increase vascular volume complications of Takayasu’s in pregnancy can include that of Hypertension and exacerbation of aortic regurgitation and congestive heart failure. Hypertension can be severe and is thought to potentially cause intrauterine growth retardation and fetal haemorrhage. Case KW is a 35 year old gravida 2 para 1 lady with a past medical history of Takayasu’s arteritis and hypothyroidism. She was diagnosed with Takayasu’s aged 28 when a thyroid scan showed carotid artery stenosis. Her medications include Prednisolone, Azathioprine and Thyroxine. Her first pregnancy was unremarkable. She remained well throughout her pregnancy and was induced with propess at 40 weeks gestation, and went on to have a normal vaginal delivery and an unremarkable puerperium. She is currently 33/40 in her second pregnancy and being managed with labetalol due to systolic BP of 140, in which her pre pregnancy systolic was 80. At 8 weeks she sustained a left hemispheric transient ischaemic event. Conclusion This case study looks at a 35 year old lady currently in her second pregnancy with Takayasu’s arteritis. The case study will discuss her ongoing antenatal care and delivery.