Wound Healing Potentials of Extarct of Gambia albidum Bark

Wounding healing potentials of ethanol and ethylacetate bark extracts of Gambia albidum was determined. The extracts were used as a suppension in olive oil in a ratio of 2:1 for topical traetment of 2cm wounds. A total of eighteen albino rats were used for the study and the albino rats were divided into three groups namely; A, B and C of six animals each. Group A and B were given ethanol and ethylacetate suppension respectively while C was given olive oil. The result showed that the ethanol suppenssion was more effective than ethylacetate in reducing the diameters of 2cm wound on the albino rats. There was a general significant increase (P<0.05) in proteinase activities, total protein, ascorbic acid and cortisol levels in both extracts but there was a general significant decrease (P<0.05) in zinc and lipid peroxiodation levels of both extracts. The study concludes that the ethanol and ethylacetate extracts were effective in enhancing wound healing but ethanol extract was more effective.