Functional tetrahydroquinoxalines from perfluoroaromatic precursors

Abstract A short series of bromo- and nitro-polyfluorobenzene derivatives gave the corresponding tetrahydroquinoxaline systems upon reaction with N , N ′-dimethylethylene diamine. This annelation strategy gives useful quantities of functionalised tetrahydroquinoxaline systems which may be interesting scaffolds for the drug discovery arena.