Subpopulations of t lymphocytes in patients with ischemic heart disease

: T-cells subpopulations were determined with theophylline test in 42 patients with the ischemic heart disease, including 31 patients with the history of myocardial infarction, and in 78 healthy volunteers. The patients' age was between 20 and 40 years and between 60 and 80 years. Defect of theophylline-sensitive fraction (suppressor T-cells and cytotoxically not specific lymphocytes in young patients has been observed. This defect gradually diminished with patients' age. Moreover, and increase in the percentage of theophylline-resistant fraction of the delayed rosettes, containing among other helper T-cells for the production of antibodies, and a decrease in the percentage of early rosette fraction containing precursor cells have been noted in the group of young patients. This defect is normalized in the group of older patients.