Hexahydro-dibenzo [a, g] quinolizine compound, its preparation, pharmaceutical compositions and uses thereof
2011
The present invention relates to a formula (I) is novel and as shown hexahydrodibenzo [a, g] quinolizine compound and derivatives thereof, enantiomers thereof, diastereomers thereof, the outer and racemic mixtures, and pharmaceutically acceptable salts thereof. The present invention also relates to a method for preparing such compounds, such compounds further nervous system diseases, in particular dopamine and serotonin receptors receptor-related diseases have better control effect. Experiments show that the biological activity, such compounds are expected to be developed into a class of potent treatment of diseases associated with dopamine receptors and serotonin receptors in particular schizophrenia, Parkinson's disease, drug addiction, migraine and other diseases new chemical entities.
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