Circulating prolactin and tumoral prolactin receptors in men with tongue cancer: a preliminary study

Pre-therapeutic circulating prolactin levels and tumoral prolactin receptors (PRLR) were determined in 25 male patients with tongue cancer. The patients were divided into PRLR positive (PRLR+) and PLRL negative (PRLR−) groups. The overall survival was statistically non-significant between these two groups of PRLR as well as when considering 2% as the cutt-off level. Moreover, no correlation was observed between PRLR status and clinicopathologic prognosticators. Furthermore, patients with 15.0 ng/ml) had unfavourable overall survival (χ 2 = 4.08, df = 1, P < 0.04) than those with normoprolactin (prolactin < 15.0 ng/ml)