Inward Rectifier K+ Currents Contribute to the Proarrhythmic Electrical Phenotype of Atria Overexpressing Cyclic Adenosine Monophosphate Response Element Modulator Isoform CREM-IbΔC-X.

Florentina Pluteanu,Matthias D. Seidl,Sabine Hamer,Beatrix Scholz,Frank U. Müller

Inward Rectifier K+ Currents Contribute to the Proarrhythmic Electrical Phenotype of Atria Overexpressing Cyclic Adenosine Monophosphate Response Element Modulator Isoform CREM-IbΔC-X.

2020

Florentina Pluteanu
Matthias D. Seidl
Sabine Hamer
Beatrix Scholz
Frank U. Müller

BACKGROUND Transgenic mice (TG) with heart‐directed overexpresion of the isoform of the transcription factor cyclic adenosine monophosphate response element modulator (CREM), CREM‐IbΔC‐X, display s...

Keywords:

Inward-rectifier potassium ion channel
Transcription factor
Cyclic adenosine monophosphate
Medicine
Response element
Atrium (architecture)
Genetically modified mouse
Cell biology
Phenotype
Gene isoform

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