Analysis of Short-term Treatment with the Phosphodiesterase Type 5 Inhibitor Tadalafil on Long Bone Development in Young Rats

Luqiang Wang,Haoruo Jia,Robert J. Tower,Michael A. Levine,Ling Qin

Analysis of Short-term Treatment with the Phosphodiesterase Type 5 Inhibitor Tadalafil on Long Bone Development in Young Rats

2018

Luqiang Wang
Haoruo Jia
Robert J. Tower
Michael A. Levine
Ling Qin

Cyclic GMP (cGMP) is an important intracellular regulator of endochondral bone growth and skeletal remodeling. Tadalafil, an inhibitor of the phosphodiesterase (PDE) type 5 (PDE5) that specifically...

Keywords:

cGMP-specific phosphodiesterase type 5
Endocrinology
Endochondral ossification
Intracellular
Regulator
Tadalafil
Endochondral bone growth
Internal medicine
Long bone
Phosphodiesterase
Biology

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