LACTOBACILLUS AND BIFIDOBACTERIUM INFLUENCE ON THE INDICES OF IMMUNE RESPONSE OF THE ORGANISM SHOWED ON THE EXPERIMENTAL MODEL

It was studied the influence of Lactobacillus and Bifidobacterium on interferonogenesis and functional activity of murine phagocytosis system cells in vivo. It was established that Bifidobacterium Bifidobacterium, Bifidobacterium longum, Lactobacillus acidophilus, Lactobacillus casei and Lactobacillus bulgaricus in vivo had activated the endogenous interferon production proved to be true by essential increase of interferon concentration in murine blood plasma. Lactobacillus acidofillus and Bifidobacterium longum have appeared the most effective inducing agent of both “early” and “late” interferon. These preparation also extended spontaneous and ridostin-induced production of interferon by spleen cells. The probiotic strains of Lactobacillus and Bifidobacterium introduction was accompanied by stimulation of oxygen-depending bactericide and absorbing activity of peritoneal macrophages. Received data testify the obtained composition on the basis of Bifidobacterium longum and Lactobacillus acidophilus is the most perspective for immune correction.