Nerve ultrasound and 3D-MR neurography suggestive of intraneural perineurioma

An 8-year-old girl presented with progressive painless right peroneal and tibial nerve palsy. A 20-year-old woman had insidious weakness of the left wrist and fingers extension. Both underwent neurophysiology (tables e-1 through e-4 on the Neurology® Web site at [Neurology.org][1]) and nerve ultrasound that showed enlargement of sciatic (figure, A) and radial nerve (figure, D–E). A 3D–magnetic resonance (MR) neurography examination detected a 20-cm-long uniform enlargement of sciatic nerve (figure, B) and a 6-cm-long fusiform enlargement of radial nerve (figure, F) with mild hyperintensity and marked contrast enhancement, suggesting intraneural perineurioma.1,2 [1]: http://neurology.org/lookup/doi/10.1212/WNL.0000000000002488