Maternal levels of alpha fetoprotein in African women

In a prospective and cross-sectional study, 147 serum samples from normal antenatal indigenous Kenyan women were analysed for alpha-fetoprotein (AFP) concentrations between 8 and 28 weeks gestation. there was progressive rise in AFP levels with gestation, most rapid between 12 and 24 weeks. There were wide variations in AFP concentrations at every gestation but no correlation was established with maternal age or parity