We should not settle for low-level evidence but should always use the best available evidence

To the editor: We would like to thank Dr. Mirza [1] for his editorial in response to our paper [2] on "Ultrasound guided conformal brachytherapy of cervix cancer: survival, patterns of failure, and late complications." He has raised several questions about our study, which we would like to address. Firstly, we would like to clarify that this study is based on data from our prospective unit database and is not, as stated by Dr. Mirza a retrospective study. This is an ethics-approved database into which baseline, treatment and outcome data about all patients referred to our unit for radiotherapy were entered prospectively. Toxicities were scored according to modified World Health Organization/Radiation Therapy Oncology Group criteria. We have reported three categories of toxicities to organs at risk, namely bladder, small and large bowel, and vagina.