Lifestyle and risk of dementia: a case-control study.

Objective To assess the lifestyle of seniors and to evaluate the risk factors of Dementia.Methods A case-control study was conducted.A total of 120 patients with dementia and 240 healthy seniors from the same community whose background matched with those of patients were enrolled in to the study.All subjects were tested neuropsychologically including MMSE and CDR.The data was analyzed by statistical technique of Chi-square test and conditional logistic regression by SPSS 15.0.Results Multiple factor analysis confirmed that playing chess,travelling,working after retirement,reading,using computer,physical excising,cognitively stimulating activities,social activities,consuming saturated fatty acids,eating seafood,daily consumption of fruits and vegetables were closely related factors to dementia with the OR values of 0.613(0.364-0.873),0.671(0.367-0.782),0.531(0.326-0.724),0.572(0.374-0.828),0.536(0.316-0.869),3.532(1.016-5.316),0.352(0.191-0.524),3.256(1.485-6.765),3.624(1.468-6.587),0.224(0.173-0.592),0.285(0.116-0.565).Conclusions A positive,joyful lifestyle combined with healthy diet may effectively reduced the risk of dementia among the elderly.