Synthesis and antibacterial activity of novel neamine derivatives.
2006
Abstract Synthesis and activity of derivatives at the O5 or O6 positions of 1- N -(( S )-4-amino-2-hydroxybutyryl)-3′,4′-dideoxyneamine, which is the neamine moiety of arbekacin, were reported. Among these results, the 5- O -aminoethylaminocarbonyl derivative showed effective activity against Staphylococcus aureus expressing a bifunctional aminoglycoside-modifying enzyme AAC(6′)-APH(2″).
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
13
References
10
Citations
NaN
KQI